HEPCIDIN DEFICIENCY IN MICE IMPAIRS WHITE ADIPOSE TISSUE BROWNING POSSIBLY DUE TO A DEFECT IN DE NOVO ADIPOGENESIS

Hepcidin deficiency in mice impairs white adipose tissue browning possibly due to a defect in de novo adipogenesis

Abstract The role of iron in the two major sites of adaptive thermogenesis, namely the beige inguinal (iWAT) and brown adipose tissues (BAT) has not been fully understood yet.Body iron levels and distribution is controlled by the iron regulatory peptide hepcidin.Here, we explored iron homeostasis and thermogenic activity in brown and beige fat in w

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The effect of group cognitive behavioral therapy on stress, anxiety, and depression of women with multiple sclerosis

Background: One of the factors that could influence the quality of life in patients with multiple sclerosis, which is usually overlooked, is its psychological aspects.Considering the increasing acceptance of complementary medicine in Vacuum Lid Seal the health system, this study was designed and conducted to determine the effect of group cognitive

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Astaxanthin Reduces Stemness Markers in BT20 and T47D Breast Cancer Stem Cells by Inhibiting Expression of Pontin and Mutant p53

Astaxanthin (AST) is a product made from marine organisms that has been used unknown as an anti-cancer supplement.It reduces pontin expression and induces apoptosis in SKBR3, a breast cancer cell line.Using Western blotting and qRT-PCR analyses, this study revealed that in the T47D and BT20 breast cancer cell lines, AST inhibits expression of ponti

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